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A new study published Monday, Dec. 3 in the Journal of Clinical Endocrinology & Metabolism, confirmed that taking a generic form of dutasteride is safe and effective in lowering sperm counts men with low counts.
The results of this study confirm that the treatment works, but it provides no benefits to men with normal sperm counts or high counts.
The study, led by Dr. Jeffrey Raber at Albert Einstein College of Medicine, compared the safety, efficacy and tolerability of levonorgestrel-progestogen (LNG-P) with dutasteride in men low sperm counts (less than 250 million/ml), and high sperm counts (more than 500 million/ml).
Levonorgestrel-progestogen was chosen because it is a similar progestogen to the pill (which has a high sperm count), and has long been used in women to Buy pantoloc control treat severe uterine fibroids.
Of 25 men from the U.S. and Canada, 11 were treated with either LNG-P or dutasteride; 14 were given LNG-P alone, and two were given nothing. The study results were dutasterid topisch kaufen then compared to follow-up sperm count measurements of men in the group treated with LNG-P and dutasteride.
The study found that in group of men who received nothing, the overall mean sperm count decreased from 2.23 million/ml to 2.08 million/ml, while the number of sperm with a normal morphology (non-fertile) decreased from 16.4% to 11.6%. In these men, the sperm count was unchanged when treated with LNG-P, while the sperm morphological abnormalities had a statistically significant decline in sperm count.
Compared with the group treated dutasteride alone, number of sperm with normal morphology decreased from 17.2% to 11.9%; the number of morphologically abnormal sperm decreased from 25.1% to 22.8%. These changes, the researchers found, were mostly due to a reduction in the number of subfertile sperm.
"The majority of men treated with oral contraceptives were taking the contraceptive pill," says Dr. David Epstein, CEO of the Luteal Biology Center, Dr. Epstein's fertility laboratory. "If these results were true for men taking LNG, cost of generic dutasteride then it would show that LNG is safe and effective in men with normal sperm counts. These results are good news, even though we don't yet know where the increase Dutas 0.5mg $124.59 - $2.08 Per pill in sperm count is coming from."
What's more, the researchers found that effectiveness of LNG-P decreased with a drop in semen volume. For those men taking LNG as their only form of birth control, the researchers found that Valsartan generic price ability.
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